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Opis

The purpose of this dissertation was: 1) to biochemically characterize how purified matrix Gla protein (MGP) functions as a calcification inhibitor using two novel in vitro calcification assays; 2) to characterize MGP s binding to apatite mineral; and 3) to characterize MGP purified from bone, cartilage, and serum using mass spectrometry. The data presented in this dissertation provide for the first time evidence of how purified MGP acts as an inhibitor of calcification and establishes that MGP accomplishes this function through direct interaction with calcium phosphate mineral.

Szczegóły książki

• Pełny tytuł: Biochemical Characterization of Matrix Gla Protein
• Podtytuł: A study of the physical and calcification inhibitory properties of matrix Gla protein.
• Autor: Francisco Villa
• Język: Angielski
• Oprawa: Miękka
• Liczba stron: 156
• EAN: 9783838324777
• ID: 07138740
• Wydawca: LAP Lambert Academic Publishing
• Waga: 249 g
• Wymiary: 220 × 150 × 9 mm
• Rok wydania: 2009

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