Zobacz książki o podobnej tematyce

Więcej informacji o Tumor Suppressor Par-4

• Dane szczegółowe
• Opis
• Ulubione w innej kategorii

Za ten zakup dostaniesz 549 punkty

Opis

Par-4 is a tumor suppressor protein first discovered and identified in 1993 by Dr. Vivek Rangnekar's laboratory in prostate cancer cells undergoing apoptosis. Par-4 (later also known as PAWR) is a naturally occurring tumor suppressor. Studies have indicated that Par-4 selectively induces apoptosis in cancer cells while leaving normal, healthy, cells unaffected. Mechanisms contributing to the cancer-selective action of Par-4 have been associated with protein kinase A activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. Par-4 is downregulated, inactivated or mutated in diverse cancers. This first of two volumes will be the first on the market on the topic of Par-4, and will provide the opportunity for researchers to discuss the future direction of studies, broaden the scope of research, and contribute a more complete understanding of the molecule's structural features, key functional domains, regulation and relevant basic and clinical/translational facets.

Szczegóły książki

• Pełny tytuł: Tumor Suppressor Par-4
• Podtytuł: Structural Features, Molecular Mechanisms and Function
• Autor: Vivek M. Rangnekar
• Język: Angielski
• Oprawa: Twarda
• Liczba stron: 323
• EAN: 9783030735715
• ISBN: 3030735710
• ID: 37628728
• Wydawca: Springer Nature Switzerland AG
• Waga: 670 g
• Wymiary: 235 × 155 × 24 mm
• Data wydania: 09. January 2022

Ulubione w innej kategorii

---

---

---