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Opis

The hologenome concept of evolution posits that the holobiont (host plus all of its associated microorganisms) with its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in consortium, function as a unique biological entity and therefore as a level of selection in evolution. Groundbreaking research during the last 10 years is the basis for the foundation for the hologenome concept of evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the number of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next with fidelity and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a way that affects the fitness of the holobiont within its environment. Beneficial microbiota protect against pathogens, provide essential nutrients, catabolize complex polysaccharides, detoxification harmful chemicals, regulate angiogenesis and blood pressure and contribute to the immune systems. The sum of these interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Under environmental stress, the microbiome can change more rapidly and by more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.

Szczegóły książki

Kategoria Książki po angielsku Mathematics & science Biology, life sciences Life sciences: general issues

• Pełny tytuł: Hologenome Concept: Human, Animal and Plant Microbiota
• Autor: Eugene Rosenberg, Ilana Zilber-Rosenberg
• Język: Angielski
• Oprawa: Twarda
• Liczba stron: 178
• EAN: 9783319042404
• ISBN: 3319042408
• ID: 02316853
• Wydawca: Springer International Publishing AG
• Waga: 438 g
• Wymiary: 165 × 233 × 18 mm
• Data wydania: 31. January 2014

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