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Opis

Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of the most exciting developments in the field, such as Fragment-based methods, are described in this book.§The book describes the latest developments in technologies that can be used to obtain the 3-D structures including the high profile structural genomics approaches being utilised worldwide. The use of 3-D protein structures in new, Fragment-based, approaches to drug discovery are described in some detail. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions. In addition, developments in computational chemistry methodology are covered together with an assessment of practical applications.

Szczegóły książki

Kategoria Książki po angielsku Technology, engineering, agriculture Industrial chemistry & manufacturing technologies Industrial chemistry

• Pełny tytuł: Structure-based Drug Discovery
• Autor: Harren Jhoti, Andrew R. Leach
• Język: Angielski
• Oprawa: Twarda
• Liczba stron: 250
• EAN: 9781402044069
• ISBN: 1402044062
• ID: 01416560
• Wydawca: Springer-Verlag New York Inc.
• Waga: 542 g
• Wymiary: 244 × 166 × 22 mm
• Data wydania: 01. May 2006

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