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Więcej informacji o Schizophrenia a psychological disorder treatment and future aspects

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Opis

New strategies for treatment of schizophrenia covers Agonists at the glycine and glutamate site of NMDA receptors include the naturally occurring amino acids glycine and D-serine. An analogue of D-serine, called D-cycloserine is also active at the glycine co-agonist site of NMDA receptors. All of these agents have been tested in schizophrenia with evidence that they can reduce negative and/or cognitive symptoms. The GLY-T1 reuptake pump is the major route of inactivation of synaptic glycine, so it is logical to explore the ability of GLY-T1 inhibitors to enhance synaptic actions of glycine, and, thus, of NMDA receptors. GLY-T1 pumps inhibit reuptake of other neurotransmitters which are blocked by a GLY-T1 inhibitor and this increases the synaptic availability of glycine and thus enhances NMDA neurotransmission.

Szczegóły książki

• Pełny tytuł: Schizophrenia a psychological disorder treatment and future aspects
• Podtytuł: Schizophrenia: The multiple personality disorder
• Autor: Ishan I. Panchal, Dhrubo Jyoti Sen, Samir K. Shah
• Język: Angielski
• Oprawa: Miękka
• Liczba stron: 64
• EAN: 9783659104473
• ID: 07044469
• Wydawca: LAP Lambert Academic Publishing
• Waga: 112 g
• Wymiary: 220 × 150 × 4 mm
• Rok wydania: 2012

Ulubione w innej kategorii

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