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Opis

The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume. The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures. The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.

Szczegóły książki

Kategoria Książki po angielsku Medicine Other branches of medicine Pharmacology

• Pełny tytuł: Issues In Risk Assessment Pb
• Autor: Committee on Risk Assessment Methodology, Commission on Life Sciences, Division on Earth and Life Studies, National Research Council, National Academy
• Język: Angielski
• Oprawa: Twarda
• Liczba stron: 374
• EAN: 9780309047869
• ISBN: 0309047862
• ID: 04576172
• Wydawca: National Academies Press
• Waga: 454 g
• Data wydania: 01. January 1993

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