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Więcej informacji o Heterocyclic Compounds: Anti-inflammatory Agents

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Opis

Inflammation is the body's attempt at self-protection to remove harmful stimuli and begin the healing process, which involves immune cells, blood vessels and molecular mediators, towards the harmful stimuli. The inflammatory response is in three different phases:(A) An acute phase(B) A sub-acute phase(C) A chronic proliferative phase The Mercapto Benzothiazole Linked 1,2,4-Oxadiazole derivatives were designed by Bioisosteric replacement designing approach and synthesized. The 2-Mercapto Benzooxazole linked 1,2,4-Oxadiazoles were designed by scaffold hopping approach and synthesised. The 2-Mercapto Benzothiazole Coupled Benzyl Triazoles compounds were designed by scaffold-Hopping approach and synthesised. All these compounds were biologically evaluated as anti inflammatory agents by targeting COX-1, COX-2, and LOX-5.

Szczegóły książki

• Pełny tytuł: Heterocyclic Compounds: Anti-inflammatory Agents
• Podtytuł: Benzothiazole, Benzooxazole, Oxadiazole and Triazole Derivatives as Anti-inflammatory Agents
• Autor: Rambabu Gundla, Naresh Kumar Katari, Satyanarayana Yatam
• Język: Angielski
• Oprawa: Miękka
• Liczba stron: 100
• EAN: 9786204736150
• ID: 38694602
• Wydawca: LAP Lambert Academic Publishing
• Waga: 167 g
• Wymiary: 220 × 150 × 6 mm
• Rok wydania: 2022

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