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Opis

The tyrosine kinases are frequently implicated in experimental as well as in human cancer. The best-studied receptor signaling system from this family is the EGF receptor. Experts in this area report on the involvement of the receptor in a variety of human tumors, outline underlying molecular mechanisms for aberrant receptor signaling in experimental systems and present the status of current therapies. A detailed analysis of EGF receptor signal transduction via expression of receptor, ligands, phosphatases and presence of other members of the receptor family will provide new information for the design of therapeutic modalities targeting this receptor system.

Szczegóły książki

Kategoria Książki po angielsku Medicine Clinical & internal medicine Diseases & disorders

• Pełny tytuł: EGF Receptor in Tumor Growth and Progression
• Autor: R.B. Lichtner, R.N. Harkins
• Język: Angielski
• Oprawa: Miękka
• Liczba stron: 258
• EAN: 9783662033937
• ISBN: 3662033933
• ID: 02646606
• Wydawca: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
• Waga: 364 g
• Wymiary: 210 × 148 × 16 mm
• Data wydania: 06. February 2013

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