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Viac informácií o knihe Retrovirus Restriction in Primates and the Discovery of TRIMCyp

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• Anotácia kniha
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Anotácia knihy

Cells derived from numerous primate species are known to resist HIV-1 infection, a finding that had limited the development of non-human primate models of AIDS. In recent years, several studies suggested that many primate-derived cell lines possess dominant factors that block infection by various retroviruses. In the work described here, one of these factors was identified as a protein named TRIM-Cyp. In addition to its potent ability to interfere with HIV infection, TRIM-Cyp also represents an important mechanism in the formation of new genes - it is a hybrid between two unrelated genes, created by the activity of a retrotransposon. TRIM-Cyp, and other TRIM5 proteins in various primates, are important determinants of retrovirus tropism, and reveal a great deal about the evolutionary arms race between retroviruses and their hosts.

Parametre knihy

• Celý názov: Retrovirus Restriction in Primates and the Discovery of TRIMCyp
• Autor: David Sayah
• Jazyk: Angličtina
• Väzba: Brožovaná
• Počet strán: 144
• EAN: 9783836471077
• ID: 07085702
• Nakladateľ: VDM Verlag Dr. Müller
• Hmotnosť: 198 g
• Rozmery: 220 × 150 × 7 mm
• Rok vydania: 2010

Obľúbené z iného súdka

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