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Book synopsis

Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive. Findings have shed new light on the mechanisms that determine the effects of stress on cognitive and affective function. Researchers have brought a wide range of techniques to bear on the study of this problem, including cutting-edge live imaging techniques, electrophysiology, glutamate release from isolated live synaptic terminals, development of transgenic and animal models and new behavioral methods. This book provides an overview of these recent findings and of the techniques used as well as a discussion of how the molecular, cellular, and functional effects of stress may trigger or precipitate neuropsychiatric disorders such as depression, schizophrenia, anxiety and PTSD.

Book details

Book category Books in English Mathematics & science Biology, life sciences Life sciences: general issues

• Full title: Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders
• Author: David Diamond, Maurizio Popoli, Gerard Sanacora
• Language: English
• Binding: Paperback
• Number of pages: 355
• EAN: 9781493946327
• ISBN: 1493946323
• ID: 14166712
• Publisher: Springer-Verlag New York Inc.
• Weight: 5621 g
• Dimensions: 235 × 155 × 21 mm
• Date of publishing: 03. September 2016

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