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Book synopsis

Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines.§This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines.

Book details

Book category Books in English Medicine Clinical & internal medicine Diseases & disorders

• Full title: Replicating Vaccines
• Subtitle: A New Generation
• Author: Philip R. Dormitzer, Christian W. Mandl, Rino Rappuoli
• Language: English
• Binding: Hardback
• Number of pages: 447
• EAN: 9783034602761
• ISBN: 3034602766
• ID: 01438662
• Publisher: Birkhauser Verlag AG
• Weight: 942 g
• Dimensions: 235 × 155 × 33 mm
• Date of publishing: 03. November 2010

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