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Book synopsis

Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activity of a specific cell protein.§Each of three sections explores mechanisms of gene regulation and expression, and presents methods and protocols for achieving specific experimental goals. Part I focuses on approaches for studying control of mRNA expression and determining target genes for a given transcription copy. Part II outlines the methods for determining how proteins can regulate each other by mediating synthesis, degradation, protein-protein interactions, and posttranslational modification. Part III explores how gene targeting techniques in mice can provide insight into protein function. This volume provides a clear, concise overview of the protocols and techniques used to examine chemically or disease-mediated alterations in gene expression in mammalian systems.

Book details

Book category Books in English Mathematics & science Biology, life sciences Life sciences: general issues

• Full title: Regulation of Gene Expression
• Author: Gary H. Perdew, Jack P. Vanden Heuvel, Jeffrey M. Peters
• Language: English
• Binding: Hardback
• Number of pages: 333
• EAN: 9781588292650
• ISBN: 1588292657
• ID: 01430319
• Publisher: Humana Press Inc.
• Weight: 673 g
• Dimensions: 235 × 155 × 31 mm
• Date of publishing: 15. September 2006

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