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Book synopsis

This is the first compilation of protein lipidation enzymes. This volume summarizes recent dramatic developments regarding enzymes responsible for protein lipidation, a process critical for a number of physiological functions, including cell proliferation and morphology. Inhibitors of protein lipidation have recently been shown to be useful as anticancer drugs. Enzymatic mechanisms, mutational analysis, and structural studies are presented. It includes the enzymatic mechanisms of protein lipidation. It also presents three-dimensional structures of protein farnesytransferase, protein geranylgeranytransferase II, and n-myristoryltransferase.

Book details

Book category Books in English Mathematics & science Biology, life sciences Biochemistry

• Full title: Protein Lipidation
• Author: Fuyuhiko Tamanoi, David S. Sigman
• Language: English
• Binding: Hardback
• Number of pages: 322
• EAN: 9780121227227
• ISBN: 0121227227
• ID: 04492900
• Publisher: Elsevier Science Publishing Co Inc
• Weight: 600 g
• Dimensions: 229 × 152 × 20 mm
• Date of publishing: 19. October 2000

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