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More about Profil' jexpressii markerov BMP gennoj seti pri narusheniyah rosta volos

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Book synopsis

Spontannye mutatsii, narushayushchie formirovanie volosyanogo pokrova, yavlyayutsya izvestnym ob"ektom izucheniya razvitiya volosyanykh follikul. Tak mutantnye geny wellhaarig (we), waved alopecia (wal) i angora (go) narushayut razvitie volos myshi, a vzaimodeystvie etikh genov privodit k fenotipicheskim effektam, ne svoystvennym gomozigotnym mysham tol'ko po odnomu iz etikh genov. Ranee bylo ustanovleno, chto myshi, nokautnye po genam Bmp2 i Bmp4, imeyut fenotip skhozhiy s fenotipom myshey linii we/we wal/wal, chto kosvenno svidetel'stvuet o vovlechenii normal'nykh alleley genov we i wal v BMP-zavisimuyu gennuyu regulyatornuyu set'. Eta rabota posvyashchena izucheniyu roli gennoy regulyatornoy seti BMP v protsesse formirovaniya volos. V issledovanii ispol'zovalis' metody prigotovleniya gistologicheskikh srezov i PTsR v real'nom vremeni. V rezul'tate raboty byli obnaruzheny i opisany izmeneniya profilya ekspressii BMP-markerov u myshey s razlichnymi tipami narusheniy tsikla volosyanykh follikul.

Book details

• Full title: Profil' jexpressii markerov BMP gennoj seti pri narusheniyah rosta volos
• Subtitle: Issledovanie myshej s mutaciyami wellhaarig, waved alopecia i angora
• Author: Igor' Nizamutdinov, Anastasiya Nesterova
• Language: Russian
• Binding: Paperback
• Number of pages: 92
• EAN: 9783659454523
• ID: 07027653
• Publisher: LAP Lambert Academic Publishing
• Weight: 155 g
• Dimensions: 220 × 150 × 6 mm
• Published: 2013

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