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Book synopsis

This book deals§with biological membranes, focuses on permeabilization and pays particular§attention to reversible permeabilization to maintain the viability and§physiological conditions of the cells.§§Selective§permeability of biological membranes also known as semipermeability, partial§permeability or differential permeability allows molecules to diffuse, pass by§passive and active or by other types of transport processes mediated by§proteins.§§The first§chapter of the book deals with the composition of biological membranes,§characterizes cellular membranes of prokaryotic, eukaryotic cells, membranes of§cellular organelles and the function of biological membranes. The second chapter provides an overview of bilayer§permeability, selectivity of permeabilization and cellular transport§processes. Chapter§3 overviews different cell manipulations that aim to make cells permeable while§maintaining not only the structural but also the functional integrity of cells.§The last chapter deals with applications, particularly with§reversible permeabilization to study macromolecular (DNA, RNA, poly-ADP ribose)§biosynthetic processes, replication, gene expression, visualization of§replicons, intermediates of chromosome condensation, genotoxic chromatin§changes, upon treatment with heavy metals and different types of irradiation.§§The interdisciplinary§aspects of the book contribute to the understanding of the structure of nucleic§acids, replicative intermediates, Okazaki fragments, RNA primer mechanism,§subphases of replication and repair synthesis, replicons, gene expression,§chromosome condensation generated a wealth of information that will attract a§wide readership. The natural audience engaged in DNA research, including§genetics, cell and molecular biology, chemistry, biochemistry, medicine,§pharmacy will find essential material in the book. §§

Book details

Book category Books in English Mathematics & science Biology, life sciences Biochemistry

• Full title: Permeability of Biological Membranes
• Author: Gaspar Banfalvi
• Language: English
• Binding: Hardback
• Number of pages: 263
• EAN: 9783319280967
• ISBN: 3319280961
• ID: 02856910
• Publisher: Springer International Publishing AG
• Weight: 5884 g
• Dimensions: 235 × 155 × 5 mm
• Date of publishing: 11. February 2016

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