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Book synopsis

Morphological and functional studies revealed a complex system of primary sensory neurons that parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel that transmits pain. *Neurogenic inflammation in historical perspective *Cardiac protection by nociceptive afferents *Molecular mechanisms of nociception *Sensory mechanisms in migraine pathophysiology *Vagal signaling of visceral inflammation *Neurogenic mechanisms in arthritis *Therapeutic implications of vanilloid-type compounds

Book details

Book category Books in English Medicine Clinical & internal medicine Diseases & disorders

• Full title: Neurogenic Inflammation in Health and Disease
• Author: Gabor Jancso
• Language: English
• Binding: Hardback
• Number of pages: 368
• EAN: 9780444532299
• ISBN: 0444532293
• ID: 04611861
• Publisher: Elsevier Science & Technology
• Weight: 830 g
• Dimensions: 240 × 165 × 23 mm
• Date of publishing: 27. November 2008

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