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Book synopsis

Different types of cardiomyopathies are associated with variable hypertrophic response. A number of growth factors are thought to play a role in pathologic cardiac remodeling. We compared the modulation of the TGF- superfamily and IGF-1 signaling pathways and their target genes, the cell cycle regulatory proteins in tachycardia-induced dilated cardiomyopathy, a model with no detectable hypertrophy and in ischemic cardiomyopathy, a model with a marked hypertrophic reaction. Tachycardiomyopathy was characterized by chambers dilation with no identifiable hypertrophy. Ischemic cardiomyopathy was characterized by eccentric hypertrophy.

Book details

• Full title: Modulation of growth factors in experimental cardiomyopathy
• Subtitle: Tachcardia-indused diated cardiomyopathy and ischemic cardiomyopathy
• Author: Maryam Mahmoudabady
• Language: English
• Binding: Paperback
• Number of pages: 124
• EAN: 9783838332611
• ID: 07003923
• Publisher: LAP Lambert Academic Publishing
• Weight: 184 g
• Dimensions: 220 × 150 × 7 mm
• Published: 2010

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