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Book synopsis

Recent technological advances in genetics pose new§challenging problems to statistical methodology. The§genetic technique of QTL mapping deals with locating§genes that influence a quantitative character of an§organism. Within the statistical framework of model§selection, existing approaches are adapted and§modifed: The search for genetic effects is extended§to interactions between genes (i.e. epistatsis),§while taking computational performance into account.§Robust statistical methods are included in order to§cope with quantitative effects that have heavy-tailed§distribution or outliers. The performance and§applicability of all methods is assessed by extensive§simulation studies and the reanalysis of previously§published genetic data sets.

Book details

Book category Books in English Mathematics & science Mathematics Probability & statistics

• Full title: Model Selection Techniques for Locating Quantitative Trait Loci
• Subtitle: Modifying the Bayesian Information Criterion for Locating Multiple Quantitative Trait Loci in Experimental Crosses
• Author: Andreas Baierl
• Language: English
• Binding: Paperback
• Number of pages: 96
• EAN: 9783838101224
• ISBN: 3838101227
• ID: 06883303
• Publisher: Sudwestdeutscher Verlag Fur Hochschulschriften AG
• Weight: 141 g
• Dimensions: 229 × 152 × 5 mm
• Date of publishing: 06. November 2008

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