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Book synopsis

This volume discusses the latest technologies used to study all aspects of Fragile-X Syndrome (FXS). The chapters in this book cover topics such as monitoring for epigenetic modifications at the FMR1 locus; modeling FXS with human pluripotent stem cells, mouse neural progenitors; mouse versus human-based models for FXS pre-clinical research; and Fragile-X associated with Tremor/Ataxia Syndrome (FXTAS). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Fragile-X Syndrome: Methods and Protocols is a valuable tool to help scientists working towards one day developing a therapeutic solution to improve the symptoms of FXS. Chapter "Induced Neurons for the Study of Neurodegenerative and Neurodevelopmental Disorders" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Book details

• Full title: Fragile-X Syndrome
• Subtitle: Methods and Protocols
• Author: Dalit Ben-Yosef, Yoav Mayshar
• Language: English
• Binding: Hardback
• Number of pages: 192
• EAN: 9781493990795
• ID: 20543965
• Publisher: Humana Press Inc.
• Weight: 624 g
• Dimensions: 254 × 178 × 17 mm
• Date of publishing: 22. March 2019

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