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Book synopsis

Timothy Gaginella and Antonio Guglietta bring together hands-on experts to critically review the many promising new areas of gastrointestinal pharmacology at the molecular level. Key chapters discuss such major themes as cyclooxygenase-2 inhibitors, the complexities of nitric oxide pathways in the gut, and the influence of cytokines on inflammatory bowel disease, as well as new opportunities for pharmacotherapy, including peptide growth factors, achykinins-particularly substance P and neurokinins-cholecystokinin receptors, and serotonin. Also examined as possible sites for treating motility disorders and visceral pain are the opioid receptors residing in the gut, and the H3-receptor agonists for treating gut inflammation and pain. Drug Development: Molecular Targets for Gastrointestinal Disease provides a comprehensive review of today's molecular pharmacological approaches to the discovery and development of novel drugs for gastrointestinal and liver diseases.

Book details

Book category Books in English Medicine Medicine: general issues Medical equipment & techniques

• Full title: Drug Development
• Subtitle: Molecular Targets for GI Diseases
• Author: Timothy S. Gaginella, Antonio Guglietta
• Language: English
• Binding: Hardback
• Number of pages: 278
• EAN: 9780896035898
• ISBN: 0896035891
• ID: 02106274
• Publisher: Humana Press Inc.
• Weight: 454 g
• Dimensions: 155 × 229 × 23 mm
• Date of publishing: 01. September 1999

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