Code: 01659903

Diverse Effects of Hypoxia on Tumor Progression

Name: Diverse Effects of Hypoxia on Tumor Progression
Brand: Springer, Berlin
SKU: 01659903
Price: 185.84 EUR
Availability: InStock

by M. Celeste Simon

Language: English
Binding: Paperback
Number of pages: 146
Publisher: Springer, Berlin, 2012
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Book synopsis

Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression. This book examines ways hypoxia promotes cancer progression by regulating various aspects of cancer biology.Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression. Although severe hypoxia is generally toxic for both normal tissue and tumors, neoplastic cells gradually adapt to prolonged hypoxia though additional genetic and genomic changes with a net result that hypoxia promotes tumor progression and therapeutic resistance. Hypoxia promotes cancer progression by regulating various aspects of cancer biology, including radiotherapy resistance, metabolism, angiogenesis and invasion/migration