You might also like

More about Defekty Mitokhondrial'nogo Genoma I Ateroskleroz

• Book details
• Synopsis
• Trending among others

You get 233 loyalty points

Book synopsis

Monografiya posvyashchena vyyasneniyu roli mutatsiy mitokhondrial'nogo genoma v formirovanii ateroskleroticheskikh porazheniy sosudistoy stenki. V ney opisan razrabotannyy avtorom s sotrudnikami novyy metod kolichestvennoy otsenki mutantnogo allelya mitokhondrial'nogo genoma, pozvolyayushchiy izuchat' assotsiatsiyu nasledstvennykh i somaticheskikh mutatsiy s patologiyami u cheloveka. S pomoshch'yu dannogo metoda podtverzhdena fokal'nost' ateroskleroticheskikh porazheniy v intime aorty cheloveka: obnaruzheny otlichiya v urovne geteroplazmii 11 mitokhondrial'nykh mutatsiy dlya raznykh uchastkov kak normal'noy, tak i porazhennoy aterosklerozom morfologicheski kartirovannoy intimy aort cheloveka. Vyyavleno, chto razlichnye tipy ateroskleroticheskikh porazheniy intimy aort i sonnykh arteriy kharakterizuyutsya opredelennym naborom pro- i antiaterogennykh mutatsiy mitokhondrial'nogo genoma. Obnaruzhena korrelyatsiya urovnya geteroplazmii nekotorykh mitokhondrial'nykh mutatsiy uchastnikov issledovaniya s vozrastom. Opisany preobladayushchie pri ateroskleroticheskikh porazheniyakh gaplotipy, sostoyashchie iz ryada mutantnykh alleley mitokhondrial'nogo genoma. Vyyavleny mazhornye gaplogruppy, kak assotsiirovanye s aterosklerozom, tak i imeyushchie antiaterogennyy effekt.

Book details

• Full title: Defekty Mitokhondrial'nogo Genoma I Ateroskleroz
• Author: Margarita Sazonova, Aleksandr Orekhov, Igor' Sobenin
• Language: Russian
• Binding: Paperback
• Number of pages: 364
• EAN: 9783639880977
• ISBN: 3639880978
• ID: 07171253
• Publisher: Palmarium Academic Publishing
• Weight: 531 g
• Dimensions: 229 × 152 × 21 mm
• Date of publishing: 07. May 2014

Trending among others

---

---

---