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More about Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C H Bonds

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Book synopsis

This thesis reports the latest developments in the direct amination of various C-H bonds using an H-Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized amines. The material outlined in this book shows how McDonald achieved C-H zincation using strong, non-nucleophilic zinc bases and subsequent electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines as the electrophilic nitrogen source. McDonald's findings are of relevance to medicinal chemistry, drug discovery and materials science. Her thesis is a source of inspiration for scientists entering the field and students beginning their PhD in a related area.

Book details

• Full title: Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C H Bonds
• Author: STACEY L. MCDONALD
• Language: English
• Binding: Paperback
• Number of pages: 144
• EAN: 9783319817675
• ISBN: 9783319817675
• ID: 19415738
• Publisher: Springer International Publishing AG
• Weight: 2642 g
• Dimensions: 235 × 155 × 10 mm
• Date of publishing: 22. April 2018

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