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Book synopsis

Osobennost'yu predstavlyaemoy monografii yavlyaetsya to, chto biodegradiruemye fragmenty polimernykh kon'yugatov BAV, obsuzhdaemye v monografii, postroeny iz -aminokislot, pri etom oni mogut obladat' sobstvennoy biologicheskoy aktivnost'yu (gormonal'noy, fermentativnoy i t. d.). Rassmotreny razlichnye varianty arkhitektury biodegradiruemykh fragmentov polimernykh nositeley BAV ot lineynykh poli-( -aminokislot) do blok-sopolimerov tipa A-V ili A-V-A i zvezdoobraznykh polimernykh kon'yugatov belkov i lizinovykh dendrimerov i ikh analogov - giperrazvetvlennykh poli-(lizinov). Osoboe vnimanie v monografii udelyaetsya strukture speyserov, svyazyvayushchikh BAV s polimernym nositelem. Pokazano, chto speysery opredelyayut kak aktivnost' kon'yugata, tak i ego sud'bu posle zaversheniya im biologicheskoy funktsii. Pravil'nyy vybor struktury speysera obespechivaet vysokuyu aktivnost' kon'yugata, bezproblemnoe razrushenie biodegradiruemoy chasti polimernogo kon'yugata i garantiruet vyvod iz organizma nedegradirumykh fragmentov kon'yugata. Monografiya rekomenduetsya spetsialistam, rabotayushchim v oblasti sinteza, izucheniya i ispol'zovaniya v meditsine, biotekhnologii i nanotekhnologii biodegradiruemykh polimernykh kon'yugatov BAV.

Book details

• Full title: Biodegradiruemye Polimernye Kon'yugaty Biologicheski Aktivnykh Veshchestv
• Author: Gennadiy Vlasov
• Language: Russian
• Binding: Paperback
• Number of pages: 172
• EAN: 9783847393962
• ISBN: 3847393960
• ID: 07170304
• Publisher: Palmarium Academic Publishing
• Weight: 259 g
• Dimensions: 229 × 152 × 10 mm
• Date of publishing: 13. May 2012

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