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Book synopsis

This volume is comprised of a multidisciplinary assessment of the interplay between asbestos and cancer as well as new research about the biology and treatment of malignant mesothelioma. Chapters on the various types of asbestos and other mineral fibers, epidemiology, history and future of asbestos-related diseases are included. Other reviews present new information about the role of asbestos-related inflammation and genetic factors, including the role of inherited mutations of BAP1 , in mesothelioma causation, as well as recent research about gene signatures, cell signaling, and epigenetic mechanisms in asbestos-related diseases. Other chapters provide updates of novel disease biomarkers and prevention, mechanistic lessons from genetically engineered mouse and 3-D models of mesothelioma tumorigenesis and therapeutic resistance. Also included are up-to-date reviews of surgical, molecularly targeted chemotherapeutic, and immunotherapeutic approaches for mesothelioma as well as an overview of legal issues.

Book details

Book category Books in English Medicine Clinical & internal medicine Diseases & disorders

• Full title: Asbestos and Mesothelioma
• Author: Joseph R. Testa
• Language: English
• Binding: Hardback
• Number of pages: 407
• EAN: 9783319535586
• ISBN: 3319535587
• ID: 15775763
• Publisher: Springer International Publishing AG
• Weight: 966 g
• Dimensions: 235 × 155 × 28 mm
• Date of publishing: 18. April 2017

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