Drosophila Melanogaster - Biosensors of Atmospheric Oxidative Stress / Najlacnejšie knihy
Drosophila Melanogaster - Biosensors of Atmospheric Oxidative Stress

Kód: 06821800

Drosophila Melanogaster - Biosensors of Atmospheric Oxidative Stress

Autor Malinda Wilson

Studies of Drosophila melanogaster have led to §molecular insights concerning biomolecular §mechanisms of biology and disease including §development, differentiation, cancer and aging. §Wild-type Drosophila, unlike vertebrate mamm ... celý popis

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Viac informácií o knihe Drosophila Melanogaster - Biosensors of Atmospheric Oxidative Stress

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Anotácia knihy

Studies of Drosophila melanogaster have led to §molecular insights concerning biomolecular §mechanisms of biology and disease including §development, differentiation, cancer and aging. §Wild-type Drosophila, unlike vertebrate mammals, §selectively retains gamma-tocopherol over alpha-§tocopherol. Urate-deficient Drosophila compared to §wild-type had similar levels of glutathione but only §50% of the ascorbate levels. Dietary §supplementation with ascorbate dramatically §increased its level while chemically-defined diets §led to rapid depletion of ascorbate in both strains. §It is concluded that Drosophila do not synthesize §ascorbate, and in this respect are similar to §humans. Wild-type and urate-deficient Drosophila §were continuously exposed to ozone. Exposure of §Drosophila to 2 ppm ozone/24hrs/day unmasked a §marked sensitivity phenotype of urate-deficient §Drosophila. Studies revealed that ascorbate §supplementation decreased ozone-induced toxicity in §Drosophila. Collectively, these data reveal the §usefulness of Drosophila as a model organism for §studying micronutrient antioxidants and their §interrelationship with ozone-induced toxicity.

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Zaradenie knihy Książki po angielsku Mathematics & science Biology, life sciences Zoology & animal sciences

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