Activation-Induced Deaminase / Najlacnejšie knihy
Activation-Induced Deaminase

Code: 02887426

Activation-Induced Deaminase

by Andrew Franklin

The mechanism of hypermutation, the process needed for B cell affinity maturation, is one of the last great mysteries in molecular biology. Activation-induced deaminase (AID) is absolutely required for hypermutation, but the mecha ... more

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Book synopsis

The mechanism of hypermutation, the process needed for B cell affinity maturation, is one of the last great mysteries in molecular biology. Activation-induced deaminase (AID) is absolutely required for hypermutation, but the mechanism by which it is recruited specifically to antibody-encoding genes remains enigmatic. This book summarizes the research on AID in the context of its central role in the affinity maturation of B cells.

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