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Book synopsis

This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate recommendations to move drug discovery programs forward.§The book introduces the current clinical practice for drug discovery and development along with the impact on early risk assessment; consolidates the tools and models to intelligently integrate existing in silico, in vitro and in vivo ADMET data; and demonstrates successful cases and lessons learned from real drug discovery and development. In short, it is a book aimed to provide a practical road map for drug discovery and development scientists to generate efficacious and safe drugs for unmet medical needs.

Book details

Book category Knihy po anglicky Technology, engineering, agriculture Industrial chemistry & manufacturing technologies Industrial chemistry

• Full title: Predictive ADMET - Integrated Approaches in Drug Discovery and Development
• Author: Jianling Wang, Laszlo Urban
• Language: English
• Binding: Hardback
• Number of pages: 624
• EAN: 9781118299920
• ISBN: 1118299922
• ID: 02722490
• Publisher: John Wiley & Sons Inc
• Weight: 996 g
• Dimensions: 241 × 156 × 39 mm
• Date of publishing: 11. April 2014

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